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Image by Adam Nieścioruk


The IRIS NeuroStudy aims to assess the long-term neuropsychiatric and neuropsychological dysfunctions associated with COVID-19 from an interdisciplinary perspective.


The proposed human subjects study leverages interdisciplinary expertise across the medical school to address the urgent need to understand the mechanisms by which the SARS-CoV-2 infection may impact long-term neuropsychiatric and neuropsychological functions. There are increasing reports of post-infection ‘brain fog’ characterized by poor concentration, anxiety, and sleep disruptions, even when physical COVID symptoms were mild.


Our IRIS study represents a landmark study in addressing these possibilities in depth. The knowledge generated will have the potential to help elucidate the root cause of ‘brain fog’ post-infection, yield new brain-based tools for diagnosing COVID-19-related neuropsychiatric sequelae, and identify selective mechanistic targets for novel interventions that will ultimately help ameliorate these effects. 

Clinical and Neurocognitive Aspects of Long Haul COVID

Stanford Department of Medicine Grand Rounds – 2021


- Dr. Aruna Subramanian, MD, Clinical Professor, Chief - Immunocompromised Host Infectious Diseases

- Dr. Leanne Williams, Ph.D., Professor and Associate Chair for Translational Neuroscience, Psychiatry, and Behavioral Sciences

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