

MEDIA
Featured Highlights

American Psychological Association (APA) Article
September 2025
'The promise of precise, personalized mental health care'
by Heather Stringer
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Coordinated, individualized tools such as brain imaging, genetic profiling, health history, and more can help determine the best treatment approach
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Nearly one third of adults with major depressive disorder fail to respond to at least two different antidepressant medications, and half of those treated for generalized anxiety disorder do not respond to first-line treatments. Numerous other mental health conditions also require that patients endure a lengthy period of treatment experimentation (Zhdanava, M., et al., The Journal of Clinical Psychiatry, Vol. 82, No. 2, 2021; Ansara, E. D., Mental Health Clinician, Vol. 10, No. 6, 2020).
“This is like getting the wrong antibiotic,” said Leanne Williams, PhD, a professor of psychiatry and behavioral sciences at Stanford University and director of Stanford Medicine’s Center for Precision Mental Health and Wellness. “In that time, the disability is developing. It is essential to find a way to get patients to the right treatment as quickly as possible to limit the chances of chronic illness.”

Stanford Engineering's
The Future of Everything Podcast
December 20, 2024
The Future of Depression Care
By Stanford Engineering Staff
This article is part of the series: The Future of Everything Podcast
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An authority on clinical depression explains how rapidly evolving imaging tools have created an explosion of knowledge about this ancient illness – and why psychiatry’s hopes are on the rise.​
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Leanne Williams is an expert in depression.
​The first thing that she wants the world to know is that depression is not some sort of character flaw, but a real illness with symptoms that can impair one’s ability to function day to day. The past decade has seen remarkable advances, she says, as functional MRI has opened new avenues of understanding depression’s mechanisms and its treatments. These are hopeful times for the science of depression, Williams tells host Russ Altman on this episode of Stanford Engineering’s The Future of Everything podcast.​
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