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The Stanford Regulating Circuits of the Brain (RBRAIN) - Ketamine study is the first of its kind to detail how brain circuits and experiences change in real time during ketamine administration.  


Little is known about the mode of action of ketamine. In this study, we are characterizing in detail how the acute administration of ketamine impacts brain circuits and experiences for each individual person. As a mechanistic trial, we focus first on healthy people.


This information is an essential foundation for then making progress in using ketamine as a personalized and safe therapeutic. Faculty members involved in this study are Drs. Leanne Williams, Brian Knutson, Karl DeisserothRobert Malenka, Laura Hack, Carolyn Rodriguez, Trisha Suppes, Boris Heifets, Peter van Roessel and Christina Khan.

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